How to Beat the Bosses
http://www.bayserve.net/~mike/duke/beatboss.html


Episode 1: L.A. Meltdown
There's a very simple way to beat the boss in Episode 1. When you enter the room where he's hiding, go in a very short distance and then immediately back out before the door closes behind you. If helps a lot to take steroids before you enter. Re-enter the room, and this time the door stays open. Lure the boss toward the door, and run out into the circular room; the boss will get stuck, and you can leisurely pump missiles into him from a distance. He'll manage to get a few shots off at you, but if you've made it this far, you shouldn't have any problems.
Here's an alternate method by Scott (the method I used to beat him) -
Go into the room and go up that ridge in the middle about half way. The boss enters the room (with his big explosion), but he won't chase you. Next, go up the ridge just enough so that you can look over it and see the boss. You should be able to start shooting him. Eventually, he will see you, and return fire. At this point, DUCK and wait till you hear no more shots. stand up and fire. He will not run after you if you don't move up too high.
Another alternate method by Jason Puchyr -
Run into the room, and as soon as the explosions indicating the arrival of the boss start hit your jet pack. If you time it right you can get above where he rises from before he rises and land on him. Presumably you still have a ton of pipe bombs left. With a little practice you can drop and detonate the pipe bombs so they hit him and not you.
So, quite easily, you can kill the first boss by standing on his head, and blowing him up. And he won't do a single bit of damage to you.


Episode 2: Lunar Apocalypse
Here's one submitted by Stefan Marx -
First, get all the stuff lying in the last room, the one with all the eggs and exploding things in it. Then walk to the big, fat door at the one end of the room and move backwards very fast. The boss will now come into the room. Shoot some rockets to him to get his interest ;-). Then run to the hole in the wall (it is on your left side when you face the door. Go through the hole and down into the water. It will be useful to put a Holoduke outside the hole. The Boss will come to the hole and try to kill you, but he can't reach you. So you can send him to hell without any risk. Pipebombs are perfect to do this but rockets work too.

Here's one submitted by Eric Loiselle -
First try to lure the boss near the wall and then start running around the room, one side to the wall. Since the room is a circle, just run backwards with the big bad guy running after you forever. And since he shoots missiles and the room is a circle, by the time his missile reaches you, it hits the wall and you get none or very minimal damage. While he's running at you, just shoot at him. He'll go down easily.

Episode 3: Shrapnel City
Here's one submitted by Dan White -
First, If you shoot the blimp that hovers over the stadium, it serves as a pinata full of useful items. Second, If you use a jetpack and fly high enough, the Boss can't get an exact shot, and there isn't a wall close enough for him to ricochet a blast at you, but you can shoot him. He dies pretty easily. Of course, you do need a jetpack for the trick to work.
And here's S.B. Henderson's method -
Shoot the blimp to collect the goodies,then go around shooting all the enemies (if any) and the cheerleaders and thier respawns (if you want). then when all is safe, well, all but the monster being there, runn onto the field and grab everything there, avoiding the rockets. Keep run mode on and jump onto the wall. Now for the fun part, run around the wall 2 or 3 times, the bosses fire will not reach you, then turn and pump some rockets or whatever into him, and as soon as his fire comes close again, run around again. And for fun, jump onto the highest point of the goals on the field, and jump over his shot while throwing pipebombs, then when you've thrown enough, run and press the button. Good fun.

MISCELLANEOUS TIPS for Beating the Bosses
(8/9/96 - From AJK) - Try using the devastator against bosses - I can complete The Stadium (3rd boss) in seconds using this method.


(8/9/96 - From Mark Kleymann) - In fighting the last two bosses, (and kind of the first one) a jet pack can be very useful, especially on the one-eyed freak. Jet pack up into the air while shooting. After you've gone up aways turn it off, then on. Keep doing this until you get down to the ground, then jet pack up again. You do have to keep an eye on your jetpack level, especially if you are not using the RPG or Devastator. This keeps their fire very innaccurate and yours will always home in on them, as long as your keep in line with them.
A better way to kill the second boss is to get him to chase you and to go into the small amount of water to the side of the room. When your underwater, turn on the jetpackand go up and shoot at the frogman. After a few second turn off the jetpack and fall right back down to relative safty. Be sure to have the jetpack and a full scuba tank.